Risk factors for persistent tomographic abnormalities at 6 months of follow-up in a cohort of hospitalized patients with moderate and severe COVID-19 living at high altitude.

Introduction: After COVID-19, functional and tomographic lung alterations may occur, but there are no studies at high altitude where, due to lower barometric pressure, there are lower levels of arterial oxygen pressure and saturation in both normal subjects and patients with respiratory disease. In this study, we evaluated the computed tomographic (CT), clinical, and functional involvement at 3 and 6 months post-hospitalization in survivors with moderate-severe COVID-19, as well the risk factors associated with abnormal lung computed tomography (ALCT) at 6 months of follow-up. Materials and methods: Prospective cohort, after hospitalization for COVID-19, of patients older than 18 years residing at high altitude. Follow-up at 3 and 6 months with lung CT, spirometry, diffusing capacity of the lung for carbon monoxide (DLCO), six-minute walk test (6MWT), and oxygen saturation (SpO2). Comparisons between ALCT and normal lung computed tomography (NLCT) groups with X2 and Mann-Whitney U test, and paired test for changes between 3 and 6 months. A multivariate analysis was performed to evaluate the variables associated with ALCT at 6-month follow-up. Results: We included 158 patients, 22.2% hospitalized in intensive care unit (ICU), 92.4% with typical COVID CT scan (peripheral, bilateral, or multifocal ground glass, with or without consolidation or findings of organizing pneumonia), and median hospitalization of 7 days. At 6 months, 53 patients (33.5%) had ALCT. There were no differences between ALCT and NLCT groups in symptoms or comorbidities on admission. ALCT patients were older and more frequently men, smokers and hospitalized in ICU. At 3 months, ALCT patients had more frequently a reduced forced vital capacity (< 80%), and lower meters walked (6MWT) and SpO2. At 6 months, all patients improved lung function with no differences between groups, but there were more dyspnea and lower exercise SpO2 in ALCT group. The variables associated with ALCT at 6 months were age, sex, ICU stay, and typical CT scan. Conclusion: At 6-month follow-up, 33.5% of patients with moderate and severe COVID had ALCT. These patients had more dyspnea and lower SpO2 in exercise. Regardless of the persistence of tomographic abnormalities, lung function and 6MWT improved. We identified the variables associated with ALCT.

The Role of Psychology in Media During the COVID-19 Pandemic: A Cross-National Study.

Dealing with COVID-19 and with the preventative measures that have been taken to mitigate the transmission of the virus causing the pandemic has posed a great challenge to the population. While psychologists have expertise with regard to preventive behavior change and to dealing with the mental health impact of measures, their expertise needs to be effectively communicated to the public. Mass media play a critical role in times of crisis, in many cases being the only source of information. While most research focuses on the importance of information content as a factor affecting psychological responses to a collective traumatic event, the way information is framed in the media is likely to influence the way health professionals are perceived as trustworthy. This study aimed to analyze the media framing of information from psychology during the COVID-19 pandemic in six countries from America and Europe, identifying the most recurrent topics in the news (n news items = 541) related to psychology and mental health. In all six countries the media address the psychological needs of the population, which vary depending on the imposed restrictions. The news content is influenced by the scientific sources used by the media. While the most prevalent topics focus on psychological risk and the need to seek mental health care, the least prevalent topics relate to counseling and behavioral guidelines for managing the psychological consequences of the pandemic. The study findings provide insight into how psychological knowledge contributes to the understanding and mitigation of COVID-19 consequences in different countries and identified fields where psychologists were consulted to respond to a health emergency. They also show a preference to consult other experts when searching for contextual or more macro-social explanations of critical situation.